Skip to main content

What the FDA labels say about taking them together

Paclitaxel and trastuzumab

Trastuzumab's FDA label of May 29, 2026 names paclitaxel in its warnings and precautions section; the paclitaxel labels PlainMeds reads (4) do not name trastuzumab.

Check it at the source: the paclitaxel FDA label on DailyMed (effective January 21, 2026, Natco Pharma USA LLC); the trastuzumab FDA label on DailyMed (effective May 29, 2026, Genentech, Inc.).

What does the paclitaxel label say about trastuzumab?

Paclitaxel's label (effective January 21, 2026) and its 3 other brand-application labels do not name trastuzumab in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Paclitaxel), Natco Pharma USA LLC, effective January 21, 2026 (SPL set a1eb16b4-285b-4e81-9c4e-1244d4a52af8), via openFDA; the full label on DailyMed

What does the trastuzumab label say about paclitaxel?

Trastuzumab label, warnings and precautions

NSABP B31 & NCCTG N9831 Median follow-up duration for NSABP B31 & NCCTG N9831 combined was 8.3 years in the AC→paclitaxel+Herceptin arm.; AC Anthracycline (doxorubicin) and cyclophosphamide. →Paclitaxel+Herceptin; 3.2% (64/2000) Includes 1 patient with fatal cardiomyopathy and 1 patient with sudden death without documented etiology.; 1.3% (21/1655)

Kanjinti label (Amgen, Inc, June 23, 2026), warnings and precautions

AC Anthracycline (doxorubicin) and cyclophosphamide. → Paclitaxel + Trastuzumab 3.2% (64/2000) Includes 1 patient with fatal cardiomyopathy and 1 patient with sudden death without documented etiology.

Source: FDA drug label (Kanjinti, BLA761073), Amgen, Inc, effective June 23, 2026 (SPL set 9a94f5b2-b84e-4987-8ea1-c4346db5a5fa), via openFDA

Source: FDA drug label (Herzuma, BLA761091), Cephalon, Inc., effective December 22, 2025 (SPL set ae71c003-883a-4cd8-ad50-e8cc9a54e971), via openFDA

Source: FDA drug label (Herceptin), Genentech, Inc., effective May 29, 2026 (SPL set 492dbdb2-077e-4064-bff3-372d6af0a7a2), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

19Paclitaxel generic labelers
0Trastuzumab generic labelers
PaclitaxelTrastuzumab
Labeled forBreast cancer, Lung cancerBreast cancer
Boxed warningYesYes
Pharmacy cost (NADAC)n/an/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?