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What the FDA labels say about taking them together

Lithium and olmesartan

Olmesartan's FDA label of September 23, 2025 names lithium in its drug interactions section; the lithium labels PlainMeds reads (4) do not name olmesartan. The olmesartan label: “Increases in serum lithium concentrations and lithium toxicity.”

Check it at the source: the lithium FDA label on DailyMed (effective December 23, 2025, Glenmark Pharmaceuticals Inc., USA); the olmesartan FDA label on DailyMed (effective September 23, 2025, Cosette Pharmaceuticals, Inc.).

What does the lithium label say about olmesartan?

Lithium's label (effective December 23, 2025) and its 3 other brand-application labels do not name olmesartan in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Lithium Carbonate), Glenmark Pharmaceuticals Inc., USA, effective December 23, 2025 (SPL set 63b3790f-a9b5-47f4-bae1-ddf8b43c13c1), via openFDA; the full label on DailyMed

What does the olmesartan label say about lithium?

Olmesartan label, drug interactions

Increases in serum lithium concentrations and lithium toxicity ( 7.4 ).

Source: FDA drug label (Benicar), Cosette Pharmaceuticals, Inc., effective September 23, 2025 (SPL set dc3f1fd4-5578-4c5d-be7b-12e3f8f3e7df), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

24Lithium generic labelers
30Olmesartan generic labelers
LithiumOlmesartan
Labeled forBipolar disorderHigh blood pressure
Boxed warningYesYes
Pharmacy cost (NADAC)$0.104 per capsule 300 mg capsule$0.0805 per tablet 20 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?