What the FDA labels say about taking them together
Norethindrone and ritonavir
Norethindrone's FDA label of January 31, 2026 names ritonavir in its drug interactions section; the ritonavir label PlainMeds reads does not name norethindrone. The norethindrone label: “Significant decreases in systemic concentrations of progestin have been noted in cases of co-administration with some HIV protease inhibitors, some HCV protease inhibitors, and some non-nucleoside reverse transcriptase …”
Check it at the source: the norethindrone FDA label on DailyMed (effective January 31, 2026, Glenmark Pharmaceuticals Inc., USA); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the norethindrone label say about ritonavir?
Norethindrone label, drug interactionsSignificant decreases in systemic concentrations of progestin have been noted in cases of co-administration with some HIV protease inhibitors (e.g., nelfinavir, ritonavir, darunavir/ritonavir, (fos)amprenavir/ritonavir, lopinavir/ritonavir, and tipranavir/ritonavir), some HCV protease inhibitors (e.g., boceprevir and telaprevir), and some non-nucleoside reverse transcriptase inhibitors (e.g., nevirapine, efavirenz).
Source: FDA drug label (Norethindrone), Glenmark Pharmaceuticals Inc., USA, effective January 31, 2026 (SPL set 0d2f8fea-3675-40d2-afd9-9fcb148dbd4b), via openFDA; the full label on DailyMed
What does the ritonavir label say about norethindrone?
Ritonavir's label (effective July 23, 2026) does not name norethindrone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Norethindrone | Ritonavir | |
|---|---|---|
| Labeled for | Birth control | HIV |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.290 per tablet 5 mg tablet | $0.607 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once