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What the FDA labels say about taking them together

Nevirapine and tacrolimus

Nevirapine's FDA label of July 15, 2026 names tacrolimus in its drug interactions section; the tacrolimus labels PlainMeds reads (4) do not name nevirapine. The nevirapine label: “Immunosuppressants: Cyclosporine, tacrolimus, sirolimus Plasma concentrations may be decreased.”

Check it at the source: the nevirapine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the tacrolimus FDA label on DailyMed (effective July 17, 2026, Stellon Biotech Inc.).

What does the nevirapine label say about tacrolimus?

Nevirapine label, drug interactions

Immunosuppressants: Cyclosporine, tacrolimus, sirolimus Plasma concentrations may be decreased.

Source: FDA drug label (Nevirapine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set c6e93829-7024-48f6-8023-da6ff27dfc0a), via openFDA; the full label on DailyMed

What does the tacrolimus label say about nevirapine?

Tacrolimus's label (effective July 17, 2026) and its 3 other brand-application labels do not name nevirapine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Tacrolimus), Stellon Biotech Inc., effective July 17, 2026 (SPL set 6b89e8a4-9f11-42e3-8e79-fe617e7c461f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

6Nevirapine generic labelers
33Tacrolimus generic labelers
NevirapineTacrolimus
Labeled forHIVOrgan transplant rejection, Eczema (atopic dermatitis)
Boxed warningYesYes
Pharmacy cost (NADAC)$0.147 per tablet 200 mg tablet$0.970 per gram 0.1% ointment
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?