What the FDA labels say about taking them together
Nevirapine and sirolimus
Nevirapine's FDA label of July 15, 2026 names sirolimus in its drug interactions section; the sirolimus labels PlainMeds reads (4) do not name nevirapine. The nevirapine label: “Immunosuppressants: Cyclosporine, tacrolimus, sirolimus Plasma concentrations may be decreased.”
Check it at the source: the nevirapine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the sirolimus FDA label on DailyMed (effective January 28, 2026, Glenmark Pharmaceuticals Inc., USA).
What does the nevirapine label say about sirolimus?
Nevirapine label, drug interactionsImmunosuppressants: Cyclosporine, tacrolimus, sirolimus Plasma concentrations may be decreased.
Source: FDA drug label (Nevirapine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set c6e93829-7024-48f6-8023-da6ff27dfc0a), via openFDA; the full label on DailyMed
What does the sirolimus label say about nevirapine?
Sirolimus's label (effective January 28, 2026) and its 3 other brand-application labels do not name nevirapine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (sirolimus), Glenmark Pharmaceuticals Inc., USA, effective January 28, 2026 (SPL set 57fb4d90-3ccb-4a69-af1e-53be83f7a504), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Nevirapine | Sirolimus | |
|---|---|---|
| Labeled for | HIV | Organ transplant rejection |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.147 per tablet 200 mg tablet | $0.723 per tablet 1 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once