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What the FDA labels say about taking them together

Nevirapine and ritonavir

Nevirapine's FDA label of July 15, 2026 names ritonavir in its drug interactions section; the ritonavir label PlainMeds reads does not name nevirapine. The nevirapine label: “Do not co-administer nevirapine with atazanavir because nevirapine substantially decreases atazanavir exposure and there is a potential risk for nevirapine-associated toxicity due to increased nevirapine exposures.”

Check it at the source: the nevirapine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).

What does the nevirapine label say about ritonavir?

Nevirapine label, drug interactions

Drug Name: Atazanavir/Ritonavir The interaction between nevirapine and the drug was evaluated in a clinical study. All other drug interactions shown are predicted.; Effect on Concentration of Nevirapine or Concomitant Drug: ↓ Atazanavir ↑ Nevirapine; Clinical Comment: Do not co-administer nevirapine with atazanavir because nevirapine substantially decreases atazanavir exposure and there is a potential risk for nevirapine-associated toxicity due to increased nevirapine exposures.

Source: FDA drug label (Nevirapine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set c6e93829-7024-48f6-8023-da6ff27dfc0a), via openFDA; the full label on DailyMed

What does the ritonavir label say about nevirapine?

Ritonavir's label (effective July 23, 2026) does not name nevirapine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

6Nevirapine generic labelers
7Ritonavir generic labelers
NevirapineRitonavir
Labeled forHIVHIV
Boxed warningYesYes
Pharmacy cost (NADAC)$0.147 per tablet 200 mg tablet$0.607 per tablet 100 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?