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What the FDA labels say about taking them together

Nevirapine and prednisone

Nevirapine's FDA label of July 15, 2026 names prednisone in its warnings and precautions section; the prednisone label PlainMeds reads does not name nevirapine. The nevirapine label: “In a clinical trial, concomitant prednisone use was associated with an increase in incidence and severity of rash during the first 6 weeks of nevirapine therapy.”

Check it at the source: the nevirapine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.); the prednisone FDA label on DailyMed (effective April 22, 2025, Hikma Pharmaceuticals USA Inc.).

What does the nevirapine label say about prednisone?

Nevirapine label, warnings and precautions

In a clinical trial, concomitant prednisone use (40 mg per day for the first 14 days of nevirapine administration) was associated with an increase in incidence and severity of rash during the first 6 weeks of nevirapine therapy.

Source: FDA drug label (Nevirapine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set c6e93829-7024-48f6-8023-da6ff27dfc0a), via openFDA; the full label on DailyMed

What does the prednisone label say about nevirapine?

Prednisone's label (effective April 22, 2025) does not name nevirapine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (PredniSONE), Hikma Pharmaceuticals USA Inc., effective April 22, 2025 (SPL set 3115aef0-fd50-4ec8-a064-3effb695f3f2), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

6Nevirapine generic labelers
45Prednisone generic labelers
NevirapinePrednisone
Labeled forHIVOsteoarthritis, Asthma, Allergies, Herpes and shingles, Leukemia, lymphoma and myeloma, Crohn's disease and ulcerative colitis, Multiple sclerosis, Eczema (atopic dermatitis), Anemia, Organ transplant rejection
Boxed warningYesNo
Pharmacy cost (NADAC)$0.147 per tablet 200 mg tablet$0.0643 per tablet 20 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?