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What the FDA labels say about taking them together

Neomycin and streptomycin

Streptomycin's FDA label of January 21, 2026 names neomycin in its boxed warning section; the neomycin label PlainMeds reads does not name streptomycin.

Check it at the source: the neomycin FDA label on DailyMed (effective February 12, 2026); the streptomycin FDA label on DailyMed (effective January 21, 2026, XGen Pharmaceuticals DJB, Inc.).

What does the neomycin label say about streptomycin?

Neomycin's label (effective February 12, 2026) does not name streptomycin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Neomycin Sulfate), Aldermed Inc., effective February 12, 2026 (SPL set 4978bb06-8b7c-9a44-e063-6294a90ac4cf), via openFDA; the full label on DailyMed

What does the streptomycin label say about neomycin?

Streptomycin label, boxed warning

THE CONCURRENT OR SEQUENTIAL USE OF OTHER NEUROTOXIC AND/OR NEPHROTOXIC DRUGS WITH STREPTOMYCIN SULFATE, INCLUDING NEOMYCIN, KANAMYCIN, GENTAMICIN, CEPHALORIDINE, PAROMOMYCIN, VIOMYCIN, POLYMYXIN B, COLISTIN, TOBRAMYCIN AND CYCLOSPORINE SHOULD BE AVOIDED.

Source: FDA drug label (Streptomycin), XGen Pharmaceuticals DJB, Inc., effective January 21, 2026 (SPL set abd1f64e-4283-4370-aae8-3666316aa36e), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Neomycin generic labelers
1Streptomycin generic labelers
NeomycinStreptomycin
Labeled forn/an/a
Boxed warningYesYes
Pharmacy cost (NADAC)$0.833 per tablet 500 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?