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What the FDA labels say about taking them together

Nefazodone and ticagrelor

Ticagrelor's FDA label of May 7, 2026 names nefazodone in its drug interactions section; the nefazodone label PlainMeds reads does not name ticagrelor. The ticagrelor label: “Avoid use of strong inhibitors of CYP3A.”

Check it at the source: the nefazodone FDA label on DailyMed (effective July 31, 2025, Teva Pharmaceuticals USA, Inc.); the ticagrelor FDA label on DailyMed (effective May 7, 2026, AstraZeneca Pharmaceuticals LP).

What does the nefazodone label say about ticagrelor?

Nefazodone's label (effective July 31, 2025) does not name ticagrelor in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Nefazodone Hydrochloride), Teva Pharmaceuticals USA, Inc., effective July 31, 2025 (SPL set 51ff7db5-aaf9-4c3c-86e6-958ebf16b60f), via openFDA; the full label on DailyMed

What does the ticagrelor label say about nefazodone?

Ticagrelor label, drug interactions

Avoid use of strong inhibitors of CYP3A (e.g., ketoconazole, itraconazole, voriconazole, clarithromycin, nefazodone, ritonavir, saquinavir, nelfinavir, indinavir, atazanavir and telithromycin) [see Clinical Pharmacology (12.3) ].

Source: FDA drug label (BRILINTA), AstraZeneca Pharmaceuticals LP, effective May 7, 2026 (SPL set f7b3f443-e83d-4bf2-0e96-023448fed9a8), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

2Nefazodone generic labelers
28Ticagrelor generic labelers
NefazodoneTicagrelor
Labeled forDepressionHeart attack and coronary artery disease, Stroke prevention
Boxed warningYesYes
Pharmacy cost (NADAC)$1.17 per tablet 100 mg tablet$0.253 per tablet 90 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?