What the FDA labels say about taking them together
Nefazodone and paclitaxel
Paclitaxel's FDA label of January 21, 2026 names nefazodone in its drug interactions section; the nefazodone label PlainMeds reads does not name paclitaxel.
Check it at the source: the nefazodone FDA label on DailyMed (effective July 31, 2025, Teva Pharmaceuticals USA, Inc.); the paclitaxel FDA label on DailyMed (effective January 21, 2026, Natco Pharma USA LLC).
What does the nefazodone label say about paclitaxel?
Nefazodone's label (effective July 31, 2025) does not name paclitaxel in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Nefazodone Hydrochloride), Teva Pharmaceuticals USA, Inc., effective July 31, 2025 (SPL set 51ff7db5-aaf9-4c3c-86e6-958ebf16b60f), via openFDA; the full label on DailyMed
What does the paclitaxel label say about nefazodone?
Paclitaxel label, drug interactionsCaution should be exercised when paclitaxel is concomitantly administered with known substrates (eg, midazolam, buspirone, felodipine, lovastatin, eletriptan, sildenafil, simvastatin, and triazolam), inhibitors (eg, atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, and telithromycin), and inducers (eg, rifampin and carbamazepine) of CYP3A4. ( See CLINICAL PHARMACOLOGY section. ) Caution should also be exercised when paclitaxel is concomitantly administered with known substrates (eg, repaglinide and rosiglitazone), inhibitors (eg, gemfibrozil), and inducers (eg, rifampin) of CYP2C8. ( See CLINICAL PHARMACOLOGY. …
Source: FDA drug label (Paclitaxel), Natco Pharma USA LLC, effective January 21, 2026 (SPL set a1eb16b4-285b-4e81-9c4e-1244d4a52af8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Nefazodone | Paclitaxel | |
|---|---|---|
| Labeled for | Depression | Breast cancer, Lung cancer |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $1.17 per tablet 100 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once