What the FDA labels say about taking them together
Fluoxetine and nebivolol
Nebivolol's FDA label of August 1, 2024 names fluoxetine in its drug interactions section; the fluoxetine label PlainMeds reads does not name nebivolol.
Check it at the source: the fluoxetine FDA label on DailyMed (effective January 8, 2026, Dista Products Company); the nebivolol FDA label on DailyMed (effective August 1, 2024, Allergan, Inc.).
What does the fluoxetine label say about nebivolol?
Fluoxetine's label (effective January 8, 2026) does not name nebivolol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Prozac), NDA018936 (Eli Lilly And Co), as published by Dista Products Company, effective January 8, 2026 (SPL set c88f33ed-6dfb-4c5e-bc01-d8e36dd97299), via openFDA; the full label on DailyMed
What does the nebivolol label say about fluoxetine?
Nebivolol label, drug interactionsUse caution when BYSTOLIC is co-administered with CYP2D6 inhibitors (quinidine, propafenone, fluoxetine, paroxetine, etc.) [see Clinical Pharmacology ( 12.5 )].
Source: FDA drug label (Bystolic), Allergan, Inc., effective August 1, 2024 (SPL set 8b8ad213-1dc8-454e-a524-075685c0e1a8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Fluoxetine | Nebivolol | |
|---|---|---|
| Labeled for | Depression, Anxiety, Bipolar disorder | High blood pressure |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0519 per capsule 40 mg capsule | $0.141 per tablet 10 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once