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What the FDA labels say about taking them together

Mycophenolic acid and sevelamer

Mycophenolic acid's FDA label of July 29, 2026 names sevelamer in its drug interactions section; the sevelamer labels PlainMeds reads (2) do not name mycophenolic acid. The mycophenolic acid label: “May decrease MPA concentrations; concomitant use is not recommended. Sevelamer: May decrease MPA concentrations; concomitant use is not recommended.”

Check it at the source: the mycophenolic acid FDA label on DailyMed (effective July 29, 2026, Novartis Pharmaceuticals Corporation); the sevelamer FDA label on DailyMed (effective November 25, 2025, Sanofi-Aventis U.S. LLC).

What does the mycophenolic acid label say about sevelamer?

Mycophenolic acid label, drug interactions

May decrease MPA concentrations; concomitant use is not recommended. ( 7.3 ) Sevelamer: May decrease MPA concentrations; concomitant use is not recommended.

Source: FDA drug label (Myfortic), Novartis Pharmaceuticals Corporation, effective July 29, 2026 (SPL set eed26501-890d-4ff6-88e7-6dbea4726e53), via openFDA; the full label on DailyMed

What does the sevelamer label say about mycophenolic acid?

Sevelamer's label (effective November 25, 2025) and its 1 other brand-application label do not name mycophenolic acid in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Sevelamer Carbonate), Sanofi-Aventis U.S. LLC, effective November 25, 2025 (SPL set 3abc32fe-1bfc-4759-8f7c-36095e221b06), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

16Mycophenolic acid generic labelers
35Sevelamer generic labelers
Mycophenolic acidSevelamer
Labeled forOrgan transplant rejectionn/a
Boxed warningYesNo
Pharmacy cost (NADAC)$0.0996 per tablet 180 mg tablet$0.214 per tablet 800 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?