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What the FDA labels say about taking them together

Mycophenolic acid and rabeprazole

Rabeprazole's FDA label of January 27, 2026 names mycophenolic acid in its drug interactions section; the mycophenolic acid label PlainMeds reads does not name rabeprazole. The rabeprazole label: “Rabeprazole can reduce the absorption of other drugs due to its effect on reducing intragastric acidity.”

Check it at the source: the mycophenolic acid FDA label on DailyMed (effective July 29, 2026, Novartis Pharmaceuticals Corporation); the rabeprazole FDA label on DailyMed (effective January 27, 2026, Waylis Therapeutics LLC).

What does the mycophenolic acid label say about rabeprazole?

Mycophenolic acid's label (effective July 29, 2026) does not name rabeprazole in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Myfortic), Novartis Pharmaceuticals Corporation, effective July 29, 2026 (SPL set eed26501-890d-4ff6-88e7-6dbea4726e53), via openFDA; the full label on DailyMed

What does the rabeprazole label say about mycophenolic acid?

Rabeprazole label, drug interactions

Clinical Impact: Rabeprazole can reduce the absorption of other drugs due to its effect on reducing intragastric acidity. Intervention: Mycophenolate mofetil (MMF): Co-administration of PPIs in healthy subjects and in transplant patients receiving MMF has been reported to reduce the exposure to the active metabolite, mycophenolic acid (MPA), possibly due to a decrease in MMF solubility at an increased gastric pH. …

Source: FDA drug label (Aciphex), Waylis Therapeutics LLC, effective January 27, 2026 (SPL set 1eb38279-0237-4967-be7a-c53a826c1138), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

16Mycophenolic acid generic labelers
20Rabeprazole generic labelers
Mycophenolic acidRabeprazole
Labeled forOrgan transplant rejectionAcid reflux and ulcers
Boxed warningYesNo
Pharmacy cost (NADAC)$0.0996 per tablet 180 mg tablet$0.224 per tablet 20 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?