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What the FDA labels say about taking them together

Mycophenolate mofetil and vonoprazan

Vonoprazan's FDA label of July 16, 2026 names mycophenolate mofetil in its drug interactions section; the mycophenolate mofetil labels PlainMeds reads (2) do not name vonoprazan. The vonoprazan label: “Other Drugs Clinical Effect Vonoprazan reduces intragastric acidity, which may decrease the absorption of drugs reducing their effectiveness.”

Check it at the source: the mycophenolate mofetil FDA label on DailyMed (effective August 5, 2026, Genentech, Inc.); the vonoprazan FDA label on DailyMed (effective July 16, 2026, Phathom Pharmaceuticals Inc.).

What does the mycophenolate mofetil label say about vonoprazan?

Mycophenolate mofetil's label (effective August 5, 2026) and its 1 other brand-application label do not name vonoprazan in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (CellCept), NDA050722 (Roche Palo), as published by Genentech, Inc., effective August 5, 2026 (SPL set 37241e87-4af4-4dc3-a1aa-ea6f20d8dc40), via openFDA; the full label on DailyMed

What does the vonoprazan label say about mycophenolate mofetil?

Vonoprazan label, drug interactions

Other Drugs (e.g., iron salts, erlotinib, dasatinib, nilotinib, mycophenolate mofetil, ketoconazole/itraconazole) Clinical Effect Vonoprazan reduces intragastric acidity [see Clinical Pharmacology (12.2) ], which may decrease the absorption of drugs reducing their effectiveness.

Source: FDA drug label (VOQUEZNA), Phathom Pharmaceuticals Inc., effective July 16, 2026 (SPL set 0cc52ac5-77ec-4d66-a770-762a1a960914), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

36Mycophenolate mofetil generic labelers
0Vonoprazan generic labelers
Mycophenolate mofetilVonoprazan
Labeled forOrgan transplant rejectionAcid reflux and ulcers
Boxed warningYesNo
Pharmacy cost (NADAC)$0.138 per capsule 250 mg capsule$22.41 per tablet 20 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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