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What the FDA labels say about taking them together

Multiple vitamins and pyridoxine

Multiple vitamins's FDA label of November 20, 2024 names pyridoxine in its drug interactions section; the pyridoxine label PlainMeds reads does not name multiple vitamins. The multiple vitamins label: “Thiamine, riboflavin, pyridoxine, niacinamide, and ascorbic acid decrease activities of erythromycin, kanamycin, streptomycin, doxycycline, and lincomycin”

Check it at the source: the multiple vitamins FDA label on DailyMed (effective November 20, 2024); the pyridoxine FDA label on DailyMed (effective October 15, 2024, Fresenius Kabi USA, LLC).

What does the multiple vitamins label say about pyridoxine?

Multiple vitamins label, drug interactions

Effect of INFUVITE PEDIATRIC on other drugs: Thiamine, riboflavin, pyridoxine, niacinamide, and ascorbic acid decrease activities of erythromycin, kanamycin, streptomycin, doxycycline, and lincomycin

Source: FDA drug label (Infuvite Adult, NDA021163), Sandoz Inc, effective November 6, 2024 (SPL set 14c7bfc5-07e8-400f-b8ff-5e4794dd2805), via openFDA

Source: FDA drug label (Infuvite Pediatric), Sandoz Inc, effective November 20, 2024 (SPL set 6d06546e-8b0a-4490-82d9-397bd902a044), via openFDA; the full label on DailyMed

What does the pyridoxine label say about multiple vitamins?

Pyridoxine's label (effective October 15, 2024) does not name multiple vitamins in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Pyridoxine Hydrochloride), Fresenius Kabi USA, LLC, effective October 15, 2024 (SPL set a56d11c0-b033-4201-85ff-fc710506481a), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Multiple vitamins generic labelers
2Pyridoxine generic labelers
Multiple vitaminsPyridoxine
Labeled forn/an/a
Boxed warningNoNo
Pharmacy cost (NADAC)n/an/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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