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What the FDA labels say about taking them together

Milsaperidone and moxifloxacin

Milsaperidone's FDA label of February 27, 2026 names moxifloxacin in its warnings and precautions section; the moxifloxacin labels PlainMeds reads (3) do not name milsaperidone.

Check it at the source: the milsaperidone FDA label on DailyMed (effective February 27, 2026, Vanda Pharmaceuticals Inc.); the moxifloxacin FDA label on DailyMed (effective March 17, 2026, Macleods Pharmaceuticals Limited).

What does the milsaperidone label say about moxifloxacin?

Milsaperidone label, warnings and precautions

Steps to Prevent or Mitigate Clinically Significant Adverse Reactions or Risks Associated with QTc Interval Prolongation The concomitant use of BYSANTI should be avoided with other drugs that prolong the QTc interval including Class 1A antiarrhythmics (e.g., quinidine, procainamide) or Class III antiarrhythmics (e.g., amiodarone, sotalol), antipsychotic drugs that prolong the QTc interval (e.g., chlorpromazine, thioridazine), antibiotics that prolong the QTc interval (e.g., gatifloxacin, moxifloxacin), or any other class of drugs known to prolong the QTc interval (e.g., pentamidine, levomethadyl acetate, methadone).

Source: FDA drug label (BYSANTI), Vanda Pharmaceuticals Inc., effective February 27, 2026 (SPL set 254a1c01-4a4c-4bdd-85d6-1f23f2e4e6f8), via openFDA; the full label on DailyMed

What does the moxifloxacin label say about milsaperidone?

Moxifloxacin's label (effective March 17, 2026) and its 2 other brand-application labels do not name milsaperidone in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Moxifloxacin), Macleods Pharmaceuticals Limited, effective March 17, 2026 (SPL set 182ecd0f-714f-42f0-9b16-fb604cf15786), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Milsaperidone generic labelers
32Moxifloxacin generic labelers
MilsaperidoneMoxifloxacin
Labeled forSchizophrenia, Bipolar disorderBacterial infections
Boxed warningYesYes
Pharmacy cost (NADAC)n/a$1.60 per mL 0.5% eye drops
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?