What the FDA labels say about taking them together
Midazolam and toremifene
Toremifene's FDA label of November 13, 2024 names midazolam in its drug interactions section; the midazolam labels PlainMeds reads (4) do not name toremifene. The toremifene label: “Following coadministration on days 6 and 18 relevant increases in midazolam and α-hydroxymidazolam Cmax and AUC were not observed.”
Check it at the source: the midazolam FDA label on DailyMed (effective January 1, 2024, Fresenius Kabi USA, LLC); the toremifene FDA label on DailyMed (effective November 13, 2024, Kyowa Kirin, Inc.).
What does the midazolam label say about toremifene?
Midazolam's label (effective January 1, 2024) and its 3 other brand-application labels do not name toremifene in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Midazolam), Fresenius Kabi USA, LLC, effective January 1, 2024 (SPL set 1cc9ba6e-fa1b-405e-9de8-720c567b2a73), via openFDA; the full label on DailyMed
What does the toremifene label say about midazolam?
Toremifene label, drug interactionsFollowing coadministration on days 6 and 18 relevant increases in midazolam and α-hydroxymidazolam Cmax and AUC were not observed.
Source: FDA drug label (Fareston), Kyowa Kirin, Inc., effective November 13, 2024 (SPL set 2cab8dd1-3a10-48e6-86ce-0e5275ed49e5), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Midazolam | Toremifene | |
|---|---|---|
| Labeled for | n/a | Breast cancer |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.233 per mL 2 mg/2 mL vial | $19.60 per tablet 60 mg tablet |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once