What the FDA labels say about taking them together
Midazolam and succinylcholine
Midazolam's FDA label of January 1, 2024 names succinylcholine in its drug interactions section; the succinylcholine labels PlainMeds reads (2) do not name midazolam. The midazolam label: “Midazolam does not protect against the characteristic circulatory changes noted after administration of succinylcholine or pancuronium and does not protect against the increased intracranial pressure noted following …”
Check it at the source: the midazolam FDA label on DailyMed (effective January 1, 2024, Fresenius Kabi USA, LLC); the succinylcholine FDA label on DailyMed (effective August 18, 2026, Hospira, Inc.).
What does the midazolam label say about succinylcholine?
Midazolam label, drug interactionsMidazolam does not protect against the characteristic circulatory changes noted after administration of succinylcholine or pancuronium and does not protect against the increased intracranial pressure noted following administration of succinylcholine.
Source: FDA drug label (Midazolam), Fresenius Kabi USA, LLC, effective January 1, 2024 (SPL set 1cc9ba6e-fa1b-405e-9de8-720c567b2a73), via openFDA; the full label on DailyMed
What does the succinylcholine label say about midazolam?
Succinylcholine's label (effective August 18, 2026) and its 1 other brand-application label do not name midazolam in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (QUELICIN), Hospira, Inc., effective August 18, 2026 (SPL set fb08161e-7711-406d-e7b3-ea4515c07983), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Midazolam | Succinylcholine | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.233 per mL 2 mg/2 mL vial | n/a |
| Shortage now | In shortage | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once