What the FDA labels say about taking them together
Methylprednisolone and theophylline
Theophylline's FDA label of March 10, 2026 names methylprednisolone in its drug interactions section; the methylprednisolone labels PlainMeds reads (3) do not name theophylline.
Check it at the source: the methylprednisolone FDA label on DailyMed (effective June 22, 2026, Mylan Pharmaceuticals Inc.); the theophylline FDA label on DailyMed (effective March 10, 2026, Strides Pharma Science Limited).
What does the methylprednisolone label say about theophylline?
Methylprednisolone's label (effective June 22, 2026) and its 2 other brand-application labels do not name theophylline in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Methylprednisolone), NDA011153 (Pfizer), as published by Mylan Pharmaceuticals Inc., effective June 22, 2026 (SPL set 22dd75d6-f89a-44f7-8ca6-b64c4e9806dd), via openFDA; the full label on DailyMed
What does the theophylline label say about methylprednisolone?
Theophylline label, drug interactionsampicilin, with or without; methylprednisolone
Source: FDA drug label (Theophylline), Strides Pharma Science Limited, effective March 10, 2026 (SPL set b7a90ccf-9c32-40cc-9008-7e55b3da4dfd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Methylprednisolone | Theophylline | |
|---|---|---|
| Labeled for | Osteoarthritis, Allergies, Herpes and shingles, Leukemia, lymphoma and myeloma, Crohn's disease and ulcerative colitis, Multiple sclerosis, Asthma, Eczema (atopic dermatitis), Anemia | Asthma |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.121 per tablet 4 mg tablet | $0.330 per tablet 300 mg tablet |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once