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What the FDA labels say about taking them together

Methylphenidate and pimozide

Pimozide's FDA label of August 12, 2026 names methylphenidate in its contraindications section; the methylphenidate labels PlainMeds reads (4) do not name pimozide.

Check it at the source: the methylphenidate FDA label on DailyMed (effective July 31, 2026, Lannett Company, LLC); the pimozide FDA label on DailyMed (effective August 12, 2026, Par Health USA, LLC).

What does the methylphenidate label say about pimozide?

Methylphenidate's label (effective July 31, 2026) and its 3 other brand-application labels do not name pimozide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (methylphenidate hydrochloride CD), Lannett Company, LLC, effective July 31, 2026 (SPL set e45c75dc-d381-475b-b649-a871c8a36e60), via openFDA; the full label on DailyMed

What does the pimozide label say about methylphenidate?

Pimozide label, contraindications

Pimozide should not be used in patients taking drugs that may, themselves, cause motor and phonic tics (e.g., pemoline, methylphenidate and amphetamines) until such patients have been withdrawn from these drugs to determine whether or not the drugs, rather than Tourette’s Disorder, are responsible for the tics.

Source: FDA drug label (Pimozide), Par Health USA, LLC, effective August 12, 2026 (SPL set 70b079e2-a1f7-4a93-8685-d60a4d7c1280), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

31Methylphenidate generic labelers
2Pimozide generic labelers
MethylphenidatePimozide
Labeled forADHDn/a
Boxed warningYesNo
Pharmacy cost (NADAC)$0.158 per tablet 10 mg tablet$1.23 per tablet 1 mg tablet
Shortage nowIn shortageNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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