What the FDA labels say about taking them together
Magnesium hydroxide and tadalafil
Tadalafil's FDA label of June 3, 2026 names magnesium hydroxide in its drug interactions section; the magnesium hydroxide label PlainMeds reads does not name tadalafil. The tadalafil label: “Antacids – Simultaneous administration of an antacid and tadalafil reduced the apparent rate of absorption of tadalafil without altering exposure (AUC) to tadalafil.”
Check it at the source: the magnesium hydroxide FDA label on DailyMed (effective August 21, 2026); the tadalafil FDA label on DailyMed (effective June 3, 2026, Eli Lilly and Company).
What does the magnesium hydroxide label say about tadalafil?
Magnesium hydroxide's label (effective August 21, 2026) does not name tadalafil in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (MiraFAST soft chews), Bayer HealthCare LLC., effective August 21, 2026 (SPL set 2cee67dd-b71f-32b8-e063-6394a90ae864), via openFDA; the full label on DailyMed
What does the tadalafil label say about magnesium hydroxide?
Tadalafil label, drug interactionsAntacids – Simultaneous administration of an antacid (magnesium hydroxide/aluminum hydroxide) and tadalafil reduced the apparent rate of absorption of tadalafil without altering exposure (AUC) to tadalafil.
Source: FDA drug label (Cialis), Eli Lilly and Company, effective June 3, 2026 (SPL set bcd8f8ab-81a2-4891-83db-24a0b0e25895), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Magnesium hydroxide | Tadalafil | |
|---|---|---|
| Labeled for | Constipation, Acid reflux and ulcers | Erectile dysfunction, Enlarged prostate (BPH), Pulmonary arterial hypertension |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0095 per mL Milk of magnesia suspension | $0.167 per tablet 20 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once