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What the FDA labels say about taking them together

Magnesium hydroxide and sotalol

Sotalol's FDA label of December 16, 2024 names magnesium hydroxide in its drug interactions section; the magnesium hydroxide label PlainMeds reads does not name sotalol. The sotalol label: “Avoid administration of oral sotalol within 2 hours of antacids containing aluminum oxide and magnesium hydroxide.”

Check it at the source: the magnesium hydroxide FDA label on DailyMed (effective August 21, 2026); the sotalol FDA label on DailyMed (effective December 16, 2024, Legacy Pharma USA, Inc.).

What does the magnesium hydroxide label say about sotalol?

Magnesium hydroxide's label (effective August 21, 2026) does not name sotalol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (MiraFAST soft chews), Bayer HealthCare LLC., effective August 21, 2026 (SPL set 2cee67dd-b71f-32b8-e063-6394a90ae864), via openFDA; the full label on DailyMed

What does the sotalol label say about magnesium hydroxide?

Sotalol label, drug interactions

Avoid administration of oral sotalol within 2 hours of antacids containing aluminum oxide and magnesium hydroxide.

Source: FDA drug label (BETAPACE), Legacy Pharma USA, Inc., effective December 16, 2024 (SPL set a6a7702f-36c9-45db-b640-453dc324baee), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Magnesium hydroxide generic labelers
18Sotalol generic labelers
Magnesium hydroxideSotalol
Labeled forConstipation, Acid reflux and ulcersAtrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)$0.0095 per mL Milk of magnesia suspension$0.0707 per tablet 80 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?