What the FDA labels say about taking them together
Magnesium hydroxide and riociguat
Riociguat's FDA label of August 13, 2026 names magnesium hydroxide in its drug interactions section; the magnesium hydroxide label PlainMeds reads does not name riociguat. The riociguat label: “Antacids such as aluminum hydroxide/magnesium hydroxide decrease riociguat absorption and should not be taken within 1 hour of taking Adempas.”
Check it at the source: the magnesium hydroxide FDA label on DailyMed (effective August 21, 2026); the riociguat FDA label on DailyMed (effective August 13, 2026, Bayer HealthCare Pharmaceuticals Inc.).
What does the magnesium hydroxide label say about riociguat?
Magnesium hydroxide's label (effective August 21, 2026) does not name riociguat in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (MiraFAST soft chews), Bayer HealthCare LLC., effective August 21, 2026 (SPL set 2cee67dd-b71f-32b8-e063-6394a90ae864), via openFDA; the full label on DailyMed
What does the riociguat label say about magnesium hydroxide?
Riociguat label, drug interactionsAntacids such as aluminum hydroxide/magnesium hydroxide decrease riociguat absorption and should not be taken within 1 hour of taking Adempas [see Clinical Pharmacology (12.3) ].
Source: FDA drug label (Adempas), Bayer HealthCare Pharmaceuticals Inc., effective August 13, 2026 (SPL set 7b57509a-3d5d-41d4-8fed-1471e26372a3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Magnesium hydroxide | Riociguat | |
|---|---|---|
| Labeled for | Constipation, Acid reflux and ulcers | Pulmonary arterial hypertension |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.0095 per mL Milk of magnesia suspension | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once