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What the FDA labels say about taking them together

Macimorelin and quinidine

Macimorelin's FDA label of February 18, 2026 names quinidine in its drug interactions section; the quinidine label PlainMeds reads does not name macimorelin. The macimorelin label: “DRUG INTERACTIONS 7.1 Drugs that Prolong QT Interval Co-administration of MACRILEN with drugs that prolong the QT interval may lead to development of torsade de pointes-type ventricular tachycardia.”

Check it at the source: the macimorelin FDA label on DailyMed (effective February 18, 2026, Aeterna Zentaris GmbH); the quinidine FDA label on DailyMed (effective February 1, 2018, Sun Pharmaceutical Industries, Inc.).

What does the macimorelin label say about quinidine?

Macimorelin label, drug interactions

DRUG INTERACTIONS 7.1 Drugs that Prolong QT Interval Co-administration of MACRILEN with drugs that prolong the QT interval (such as antipsychotic medications (e.g., chlorpromazine, haloperidol, thioridazine, ziprasidone), antibiotics (e.g., moxifloxacin), Class 1A (e.g., quinidine, procainamide) and Class III (e.g., amiodarone, sotalol) antiarrhythmic medications or any other medications known to prolong the QT interval) may lead to development of torsade de pointes-type ventricular tachycardia.

Source: FDA drug label (Macrilen), Aeterna Zentaris GmbH, effective February 18, 2026 (SPL set aeb30f1a-4815-47ae-a2cb-b6b4e26372e1), via openFDA; the full label on DailyMed

What does the quinidine label say about macimorelin?

Quinidine's label (effective February 1, 2018) does not name macimorelin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Quinidine Gluconate), Sun Pharmaceutical Industries, Inc., effective February 1, 2018 (SPL set 5023f053-fcc4-4c2c-aa59-9ec198ad185e), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Macimorelin generic labelers
4Quinidine generic labelers
MacimorelinQuinidine
Labeled forn/aAtrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$4.92 per tablet 324 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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