What the FDA labels say about taking them together
Lovastatin and siltuximab
Siltuximab's FDA label of August 27, 2024 names lovastatin in its drug interactions section; the lovastatin label PlainMeds reads does not name siltuximab. The siltuximab label: “Exercise caution when SYLVANT is co-administered with CYP3A4 substrate drugs where a decrease in effectiveness would be undesirable.”
Check it at the source: the lovastatin FDA label on DailyMed (effective May 6, 2026, Lupin Pharmaceuticals, Inc.); the siltuximab FDA label on DailyMed (effective August 27, 2024).
What does the lovastatin label say about siltuximab?
Lovastatin's label (effective May 6, 2026) does not name siltuximab in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lovastatin), Lupin Pharmaceuticals, Inc., effective May 6, 2026 (SPL set df7ddf4f-d569-431e-81f1-9129d7043150), via openFDA; the full label on DailyMed
What does the siltuximab label say about lovastatin?
Siltuximab label, drug interactionsExercise caution when SYLVANT is co-administered with CYP3A4 substrate drugs where a decrease in effectiveness would be undesirable (e.g., oral contraceptives, lovastatin, atorvastatin).
Source: FDA drug label (Sylvant), Recordati Rare Diseases, Inc., effective August 27, 2024 (SPL set 8d663642-f52e-49c0-a023-2da083fdfc0b), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lovastatin | Siltuximab | |
|---|---|---|
| Labeled for | High cholesterol, Heart attack and coronary artery disease | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0436 per tablet 20 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once