What the FDA labels say about taking them together
Lorazepam and scopolamine
Lorazepam's FDA label (Lorazepam) of April 10, 2024 names scopolamine in its drug interactions section; the scopolamine label PlainMeds reads does not name lorazepam. The lorazepam label: “When scopolamine is used concomitantly with injectable lorazepam, an increased incidence of sedation, hallucinations and irrational behavior has been observed.”
Check it at the source: the lorazepam FDA label on DailyMed (effective July 9, 2025, Bausch Health US LLC); the scopolamine FDA label on DailyMed (effective June 10, 2025, Baxter Healthcare Corporation).
What does the lorazepam label say about scopolamine?
Lorazepam label (Hikma Pharmaceuticals USA Inc., April 10, 2024), drug interactionsWhen scopolamine is used concomitantly with injectable lorazepam, an increased incidence of sedation, hallucinations and irrational behavior has been observed.
Source: FDA drug label (Lorazepam, NDA018140), Hikma Pharmaceuticals USA Inc., effective April 10, 2024 (SPL set 4084fa74-9fd2-45ef-9d56-27bfa31d4e46), via openFDA
Source: FDA drug label (Ativan), Bausch Health US LLC, effective July 9, 2025 (SPL set 89057c93-8155-4040-acec-64e877bd2b4c), via openFDA; the full label on DailyMed
What does the scopolamine label say about lorazepam?
Scopolamine's label (effective June 10, 2025) does not name lorazepam in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Transderm Scop), Baxter Healthcare Corporation, effective June 10, 2025 (SPL set b877a694-a1d0-4280-937a-a06820b12a88), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lorazepam | Scopolamine | |
|---|---|---|
| Labeled for | Anxiety | Nausea and vomiting |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0344 per tablet 0.5 mg tablet | $4.34 per patch 1 mg/3 day patch |
| Shortage now | In shortage | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once