What the FDA labels say about taking them together
Loperamide and selumetinib
Selumetinib's FDA label of May 26, 2026 names loperamide in its warnings and precautions section; the loperamide label PlainMeds reads does not name selumetinib. The selumetinib label: “Gastrointestinal Toxicity: Advise patients to start an anti-diarrheal agent immediately after the first episode of loose stool and to increase fluid intake.”
Check it at the source: the loperamide FDA label on DailyMed (effective June 3, 2026, Aurobindo Pharma Limited); the selumetinib FDA label on DailyMed (effective May 26, 2026, AstraZeneca Pharmaceuticals LP).
What does the loperamide label say about selumetinib?
Loperamide's label (effective June 3, 2026) does not name selumetinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Loperamide Hydrochloride), Aurobindo Pharma Limited, effective June 3, 2026 (SPL set 8e4004be-bf79-4631-9e38-c4e7b6726313), via openFDA; the full label on DailyMed
What does the selumetinib label say about loperamide?
Selumetinib label, warnings and precautionsGastrointestinal Toxicity: Advise patients to start an anti-diarrheal agent immediately after the first episode of loose stool and to increase fluid intake.
Source: FDA drug label (KOSELUGO), AstraZeneca Pharmaceuticals LP, effective May 26, 2026 (SPL set 7d042c61-f28f-4ab5-ab10-d7558c0d49ff), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Loperamide | Selumetinib | |
|---|---|---|
| Labeled for | Diarrhea | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0549 per capsule 2 mg capsule | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once