What the FDA labels say about taking them together
Loperamide and nintedanib
Nintedanib's FDA label of November 20, 2025 names loperamide in its warnings and precautions section; the loperamide label PlainMeds reads does not name nintedanib. The nintedanib label: “Treat diarrhea at first signs with adequate hydration and antidiarrheal medication (e.g., loperamide), and consider dose reduction or treatment interruption if diarrhea continues.”
Check it at the source: the loperamide FDA label on DailyMed (effective June 3, 2026, Aurobindo Pharma Limited); the nintedanib FDA label on DailyMed (effective November 20, 2025, Boehringer Ingelheim Pharmaceuticals, Inc.).
What does the loperamide label say about nintedanib?
Loperamide's label (effective June 3, 2026) does not name nintedanib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Loperamide Hydrochloride), Aurobindo Pharma Limited, effective June 3, 2026 (SPL set 8e4004be-bf79-4631-9e38-c4e7b6726313), via openFDA; the full label on DailyMed
What does the nintedanib label say about loperamide?
Nintedanib label, warnings and precautionsTreat diarrhea at first signs with adequate hydration and antidiarrheal medication (e.g., loperamide), and consider dose reduction or treatment interruption if diarrhea continues [see Dosage and Administration (2.4) ].
Source: FDA drug label (Ofev), Boehringer Ingelheim Pharmaceuticals, Inc., effective November 20, 2025 (SPL set da1c9f37-779e-4682-816f-93d0faa4cfc9), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Loperamide | Nintedanib | |
|---|---|---|
| Labeled for | Diarrhea | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0549 per capsule 2 mg capsule | $13.46 per capsule 150 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once