What the FDA labels say about taking them together
Lomitapide and tamoxifen
Lomitapide's FDA label of March 30, 2026 names tamoxifen in its warnings and precautions section; the tamoxifen labels PlainMeds reads (2) do not name lomitapide.
Check it at the source: the lomitapide FDA label on DailyMed (effective March 30, 2026, Chiesi USA, Inc.); the tamoxifen FDA label on DailyMed (effective December 18, 2025, Actavis Pharma, Inc.).
What does the lomitapide label say about tamoxifen?
Lomitapide label, warnings and precautionsExercise caution when using JUXTAPID with other medications known to have potential for hepatotoxicity, such as isotretinoin, amiodarone, acetaminophen (>4 g/day for ≥3 days/week), methotrexate, tetracyclines, and tamoxifen.
Source: FDA drug label (Juxtapid), Chiesi USA, Inc., effective March 30, 2026 (SPL set 61a0be9d-ee58-43e0-b5cb-141011835081), via openFDA; the full label on DailyMed
What does the tamoxifen label say about lomitapide?
Tamoxifen's label (effective December 18, 2025) and its 1 other brand-application label do not name lomitapide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Tamoxifen Citrate), Actavis Pharma, Inc., effective December 18, 2025 (SPL set 9b8a4211-120f-4981-ad69-928accb97637), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lomitapide | Tamoxifen | |
|---|---|---|
| Labeled for | High cholesterol | Breast cancer |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | $0.277 per tablet 20 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once