What the FDA labels say about taking them together
Lithium and meclofenamate
Meclofenamate's FDA label of April 15, 2026 names lithium in its drug interactions section; the lithium labels PlainMeds reads (4) do not name meclofenamate. The meclofenamate label: “Lithium NSAIDs have produced an elevation of plasma lithium levels and a reduction in renal lithium clearance.”
Check it at the source: the lithium FDA label on DailyMed (effective December 23, 2025, Glenmark Pharmaceuticals Inc., USA); the meclofenamate FDA label on DailyMed (effective April 15, 2026, Mylan Pharmaceuticals Inc.).
What does the lithium label say about meclofenamate?
Lithium's label (effective December 23, 2025) and its 3 other brand-application labels do not name meclofenamate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lithium Carbonate), Glenmark Pharmaceuticals Inc., USA, effective December 23, 2025 (SPL set 63b3790f-a9b5-47f4-bae1-ddf8b43c13c1), via openFDA; the full label on DailyMed
What does the meclofenamate label say about lithium?
Meclofenamate label, drug interactionsLithium NSAIDs have produced an elevation of plasma lithium levels and a reduction in renal lithium clearance.
Source: FDA drug label (Meclofenamate Sodium), Mylan Pharmaceuticals Inc., effective April 15, 2026 (SPL set 96f19af4-de8f-4fd7-90d8-55fe6ebdd81d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lithium | Meclofenamate | |
|---|---|---|
| Labeled for | Bipolar disorder | Fever, Pain, Rheumatoid arthritis, Osteoarthritis |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.104 per capsule 300 mg capsule | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once