What the FDA labels say about taking them together
Lisinopril and octreotide
Octreotide's FDA label (Mycapssa) of July 24, 2025 names lisinopril in its drug interactions section; the lisinopril labels PlainMeds reads (2) do not name octreotide. The octreotide label: “Lisinopril: bioavailability may be increased, monitor patient's blood pressure and adjust dose of lisinopril if needed ( 7 ).”
Check it at the source: the lisinopril FDA label on DailyMed (effective January 2, 2025, Upsher-Smith Laboratories, LLC); the octreotide FDA label on DailyMed (effective July 22, 2026, Novartis Pharmaceuticals Corporation).
What does the lisinopril label say about octreotide?
Lisinopril's label (effective January 2, 2025) and its 1 other brand-application label do not name octreotide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Zestril), NDA019777 (Twi Pharms), as published by Upsher-Smith Laboratories, LLC, effective January 2, 2025 (SPL set 838c2d78-d2d8-4981-9ec9-e50ef9e1a5d8), via openFDA; the full label on DailyMed
What does the octreotide label say about lisinopril?
Mycapssa label (Chiesi USA, Inc., July 24, 2025), drug interactionsLisinopril: bioavailability may be increased, monitor patient's blood pressure and adjust dose of lisinopril if needed ( 7 ).
Source: FDA drug label (Mycapssa, NDA208232), Chiesi USA, Inc., effective July 24, 2025 (SPL set 58d80bc6-bdfb-4908-93e7-aace447c8d1a), via openFDA
Source: FDA drug label (Sandostatin), Novartis Pharmaceuticals Corporation, effective July 22, 2026 (SPL set 4e2c9856-1836-49f0-9472-4dbeeb408f39), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lisinopril | Octreotide | |
|---|---|---|
| Labeled for | High blood pressure, Heart attack and coronary artery disease, Heart failure | Diarrhea |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0254 per tablet 20 mg tablet | $2.53 per mL 100 mcg/mL vial |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once