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What the FDA labels say about taking them together

Liraglutide and metformin

Liraglutide's FDA label of October 14, 2025 names metformin in its warnings and precautions section; the metformin labels PlainMeds reads (3) do not name liraglutide. The liraglutide label: “In pediatric patients 10 years of age and older, the risk of hypoglycemia was higher with VICTOZA regardless of insulin and/or metformin use.”

Check it at the source: the liraglutide FDA label on DailyMed (effective October 14, 2025, Novo Nordisk); the metformin FDA label on DailyMed (effective September 3, 2026, Granules India Ltd).

What does the liraglutide label say about metformin?

Liraglutide label, warnings and precautions

In pediatric patients 10 years of age and older, the risk of hypoglycemia was higher with VICTOZA regardless of insulin and/or metformin use.

Source: FDA drug label (Victoza), Novo Nordisk, effective October 14, 2025 (SPL set 5a9ef4ea-c76a-4d34-a604-27c5b505f5a4), via openFDA; the full label on DailyMed

What does the metformin label say about liraglutide?

Metformin's label (effective September 3, 2026) and its 2 other brand-application labels do not name liraglutide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (METFORMIN HYDROCHLORIDE), Granules India Ltd, effective September 3, 2026 (SPL set 73197cb5-3e23-4ac0-b189-f9bc848bce66), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

9Liraglutide generic labelers
80Metformin generic labelers
LiraglutideMetformin
Labeled forType 2 diabetes, Heart attack and coronary artery disease, Weight managementType 2 diabetes
Boxed warningYesYes
Pharmacy cost (NADAC)$31.41 per mL 2-pak 18 mg/3 mL$0.0145 per tablet 500 mg tablet
Shortage nowIn shortageNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?