What the FDA labels say about taking them together
Lidocaine and metyrosine
Metyrosine's FDA label of July 1, 2021 names lidocaine in its warnings section; the lidocaine labels PlainMeds reads (4) do not name metyrosine.
Check it at the source: the lidocaine FDA label on DailyMed (effective May 13, 2024, Fresenius Kabi USA, LLC); the metyrosine FDA label on DailyMed (effective July 1, 2021, Bausch Health US, LLC).
What does the lidocaine label say about metyrosine?
Lidocaine's label (effective May 13, 2024) and its 3 other brand-application labels do not name metyrosine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Xylocaine MPF), Fresenius Kabi USA, LLC, effective May 13, 2024 (SPL set d5e0d06f-ba1e-44d4-aa89-39d6c146dc23), via openFDA; the full label on DailyMed
What does the metyrosine label say about lidocaine?
Metyrosine label, warningsIn addition, life-threatening arrhythmias may occur during anesthesia and surgery, and may require treatment with a beta-blocker or lidocaine.
Source: FDA drug label (Demser), Bausch Health US, LLC, effective July 1, 2021 (SPL set 32fb2f2f-34b5-4cd5-9145-c3ab37c5ca92), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lidocaine | Metyrosine | |
|---|---|---|
| Labeled for | Pain | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.154 per gram 5% ointment | n/a |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once