What the FDA labels say about taking them together
Levodopa and rotigotine
Rotigotine's FDA label of June 24, 2025 names levodopa in its warnings and precautions section; the levodopa label PlainMeds reads does not name rotigotine.
Check it at the source: the levodopa FDA label on DailyMed (effective July 20, 2026, Merz Pharmaceuticals, LLC); the rotigotine FDA label on DailyMed (effective June 24, 2025, UCB, Inc.).
What does the levodopa label say about rotigotine?
Levodopa's label (effective July 20, 2026) does not name rotigotine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Inbrija), Merz Pharmaceuticals, LLC, effective July 20, 2026 (SPL set 077c0f39-a3a2-4b2b-a184-09131889dcfb), via openFDA; the full label on DailyMed
What does the rotigotine label say about levodopa?
Rotigotine label, warnings and precautionsDyskinesia NEUPRO may potentiate the dopaminergic side effects of levodopa and may cause or exacerbate pre-existing dyskinesia.
Source: FDA drug label (Neupro), NDA021829 (Ucb Inc), as published by UCB, Inc., effective June 24, 2025 (SPL set 939e28c5-f3a9-42c0-9a2d-8d471d82a6e0), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Levodopa | Rotigotine | |
|---|---|---|
| Labeled for | Parkinson's disease | Parkinson's disease |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $28.29 per patch 1 mg/24 hr patch |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once