What the FDA labels say about taking them together
Levamlodipine and simvastatin
Levamlodipine's FDA label of December 11, 2024 names simvastatin in its drug interactions section; the simvastatin label PlainMeds reads does not name levamlodipine. The levamlodipine label: “Amlodipine on Other Drugs Simvastatin Co-administration of simvastatin with amlodipine increases the systemic exposure of simvastatin.”
Check it at the source: the levamlodipine FDA label on DailyMed (effective December 11, 2024, CSPC Ouyi Pharmaceutical Co. Ltd); the simvastatin FDA label on DailyMed (effective March 28, 2025, Organon LLC).
What does the levamlodipine label say about simvastatin?
Levamlodipine label, drug interactionsAmlodipine on Other Drugs Simvastatin Co-administration of simvastatin with amlodipine increases the systemic exposure of simvastatin.
Source: FDA drug label (Conjupri), CSPC Ouyi Pharmaceutical Co. Ltd, effective December 11, 2024 (SPL set c3cca66e-348a-43e8-8f96-e995104dae3d), via openFDA; the full label on DailyMed
What does the simvastatin label say about levamlodipine?
Simvastatin's label (effective March 28, 2025) does not name levamlodipine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ZOCOR), Organon LLC, effective March 28, 2025 (SPL set 8f55d5de-5a4f-4a39-8c84-c53976dd6af9), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Levamlodipine | Simvastatin | |
|---|---|---|
| Labeled for | High blood pressure | Heart attack and coronary artery disease, High cholesterol, High triglycerides |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.0321 per tablet 20 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once