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What the FDA labels say about taking them together

Levamlodipine and sildenafil

Levamlodipine's FDA label of December 11, 2024 names sildenafil in its drug interactions section; the sildenafil labels PlainMeds reads (4) do not name levamlodipine. The levamlodipine label: “Sildenafil Monitor for hypotension when sildenafil is co-administered with amlodipine.”

Check it at the source: the levamlodipine FDA label on DailyMed (effective December 11, 2024, CSPC Ouyi Pharmaceutical Co. Ltd); the sildenafil FDA label on DailyMed (effective November 17, 2023, Viatris Specialty LLC).

What does the levamlodipine label say about sildenafil?

Levamlodipine label, drug interactions

Sildenafil Monitor for hypotension when sildenafil is co-administered with amlodipine [see Clinical Pharmacology ( 12.2 )].

Source: FDA drug label (Conjupri), CSPC Ouyi Pharmaceutical Co. Ltd, effective December 11, 2024 (SPL set c3cca66e-348a-43e8-8f96-e995104dae3d), via openFDA; the full label on DailyMed

What does the sildenafil label say about levamlodipine?

Sildenafil's label (effective November 17, 2023) and its 3 other brand-application labels do not name levamlodipine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Viagra), Viatris Specialty LLC, effective November 17, 2023 (SPL set d905dc8d-917f-4ea3-a4ee-a1ecf6967d4e), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Levamlodipine generic labelers
60Sildenafil generic labelers
LevamlodipineSildenafil
Labeled forHigh blood pressureErectile dysfunction, Pulmonary arterial hypertension
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.132 per tablet 100 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?