What the FDA labels say about taking them together
Letermovir and repaglinide
Letermovir's FDA label of January 14, 2026 names repaglinide in its drug interactions section; the repaglinide label PlainMeds reads does not name letermovir. The letermovir label: “When PREVYMIS is co-administered with glyburide, repaglinide, or rosiglitazone, frequently monitor glucose concentrations. When PREVYMIS is co-administered with cyclosporine, use of repaglinide is not recommended.”
Check it at the source: the letermovir FDA label on DailyMed (effective January 14, 2026, Merck Sharp & Dohme LLC); the repaglinide FDA label on DailyMed (effective May 2, 2025, Chartwell RX, LLC).
What does the letermovir label say about repaglinide?
Letermovir label, drug interactionsConcomitant Drug Class and/or Clearance Pathway/Drug Name: Examples: glyburide, repaglinide, rosiglitazone; Effect on Concentration ↓ =decrease, ↑ =increase: ↑ glyburide ↑ repaglinide ↑ rosiglitazone; Clinical Comments: When PREVYMIS is co-administered with glyburide, repaglinide, or rosiglitazone, frequently monitor glucose concentrations. When PREVYMIS is co-administered with cyclosporine, use of repaglinide is not recommended.
Source: FDA drug label (PREVYMIS), Merck Sharp & Dohme LLC, effective January 14, 2026 (SPL set 1b49df80-be4f-47e0-a0b7-123f3e69395b), via openFDA; the full label on DailyMed
What does the repaglinide label say about letermovir?
Repaglinide's label (effective May 2, 2025) does not name letermovir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Repaglinide), Chartwell RX, LLC, effective May 2, 2025 (SPL set cb995e92-295e-4638-a064-978211f5afe1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Letermovir | Repaglinide | |
|---|---|---|
| Labeled for | n/a | Type 2 diabetes |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.0987 per tablet 1 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once