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What the FDA labels say about taking them together

Lenacapavir and triazolam

Lenacapavir's FDA label of August 27, 2026 names triazolam in its drug interactions section; the triazolam label PlainMeds reads does not name lenacapavir.

Check it at the source: the lenacapavir FDA label on DailyMed (effective August 27, 2026, Gilead Sciences, Inc.); the triazolam FDA label on DailyMed (effective July 10, 2026, Mylan Pharmaceuticals Inc.).

What does the lenacapavir label say about triazolam?

Lenacapavir label, drug interactions

Concomitant Drug Class/Drug Name: Sedatives/Hypnotics: midazolam (oral) triazolam; Effect on Concentration ↑ = Increase, ↓ = Decrease.: ↑ midazolam (oral) ↑ triazolam; Clinical Comment: Use with caution when midazolam or triazolam is concomitantly administered with SUNLENCA

Source: FDA drug label (Sunlenca), Gilead Sciences, Inc., effective August 27, 2026 (SPL set e5652804-29c4-40d7-aeb2-0142ed2a7b5b), via openFDA; the full label on DailyMed

What does the triazolam label say about lenacapavir?

Triazolam's label (effective July 10, 2026) does not name lenacapavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Triazolam), NDA017892 (Pfizer), as published by Mylan Pharmaceuticals Inc., effective July 10, 2026 (SPL set 5add318e-11b9-42f8-b052-0d8cebb32fcf), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Lenacapavir generic labelers
7Triazolam generic labelers
LenacapavirTriazolam
Labeled forHIVInsomnia
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.308 per tablet 0.25 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?