What the FDA labels say about taking them together
Lenacapavir and lovastatin
Lenacapavir's FDA label of August 27, 2026 names lovastatin in its drug interactions section; the lovastatin label PlainMeds reads does not name lenacapavir. The lenacapavir label: “Initiate lovastatin and simvastatin with the lowest starting dose and titrate carefully while monitoring for safety (e.g., myopathy).”
Check it at the source: the lenacapavir FDA label on DailyMed (effective August 27, 2026, Gilead Sciences, Inc.); the lovastatin FDA label on DailyMed (effective May 6, 2026, Lupin Pharmaceuticals, Inc.).
What does the lenacapavir label say about lovastatin?
Lenacapavir label, drug interactionsConcomitant Drug Class/Drug Name: HMG-CoA Reductase Inhibitors: lovastatin simvastatin; Effect on Concentration ↑ = Increase, ↓ = Decrease.: ↑ lovastatin ↑ simvastatin; Clinical Comment: Initiate lovastatin and simvastatin with the lowest starting dose and titrate carefully while monitoring for safety (e.g., myopathy).
Source: FDA drug label (Sunlenca), Gilead Sciences, Inc., effective August 27, 2026 (SPL set e5652804-29c4-40d7-aeb2-0142ed2a7b5b), via openFDA; the full label on DailyMed
What does the lovastatin label say about lenacapavir?
Lovastatin's label (effective May 6, 2026) does not name lenacapavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lovastatin), Lupin Pharmaceuticals, Inc., effective May 6, 2026 (SPL set df7ddf4f-d569-431e-81f1-9129d7043150), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lenacapavir | Lovastatin | |
|---|---|---|
| Labeled for | HIV | High cholesterol, Heart attack and coronary artery disease |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.0436 per tablet 20 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once