Leflunomide · larger labeled portfolio than Alosetron
SPL labels Leflunomide + Alosetron as minor; Leflunomide 20 / Alosetron 9 in that band.
Mechanism on file: Leflunomide makes your body break down alosetron faster, which lowers the amount of medicine in your blood.
FDA SPL severity: Minor
Leflunomide + Alosetron · SPL mechanism field
Leflunomide makes your body break down alosetron faster, which lowers the amount of medicine in your blood.
Minor band excerpt · Leflunomide with Alosetron
In patients taking leflunomide, exposure of drugs metabolized by CYP1A2 (e.g., alosetron, duloxetine, theophylline, tizanidine) may be reduced.
Leflunomide · 20 SPL pairs (broader portfolio than Alosetron)
- Atorvastatin minor
- Cimetidine minor
- Ciprofloxacin minor
- Duloxetine minor
Alosetron · 9 minor + 12 total pairs
- Cimetidine minor
- Eluxadoline minor
- Estradiol minor
- Fluvoxamine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.