What the FDA labels say about taking them together
Lansoprazole and theophylline
Lansoprazole's FDA label of June 24, 2025 names theophylline in its drug interactions (prescription label) section; the theophylline label PlainMeds reads does not name lansoprazole. The lansoprazole label: “Increased clearance of theophylline.”
Check it at the source: the lansoprazole FDA label on DailyMed (effective June 24, 2025, L. Perrigo Company); the theophylline FDA label on DailyMed (effective March 10, 2026, Strides Pharma Science Limited).
What does the lansoprazole label say about theophylline?
Lansoprazole label, drug interactions (prescription label)Theophylline Clinical Impact: Increased clearance of theophylline. Intervention: Individual patients may require additional titration of their theophylline dosage when PREVACID or PREVACID SoluTab is started or stopped to ensure clinically effective blood concentrations.
Source: FDA drug label (Prevacid 24 HR), L. Perrigo Company, effective June 24, 2025 (SPL set 205c9c1e-b422-4e86-a4b0-714b608adc19), via openFDA; the full label on DailyMed
What does the theophylline label say about lansoprazole?
Theophylline's label (effective March 10, 2026) does not name lansoprazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Theophylline), Strides Pharma Science Limited, effective March 10, 2026 (SPL set b7a90ccf-9c32-40cc-9008-7e55b3da4dfd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lansoprazole | Theophylline | |
|---|---|---|
| Labeled for | Acid reflux and ulcers | Asthma |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.106 per capsule 30 mg capsule | $0.330 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once