What the FDA labels say about taking them together
Lansoprazole and sucralfate
Lansoprazole's FDA label of June 24, 2025 names sucralfate in its drug interactions (prescription label) section; the sucralfate labels PlainMeds reads (2) do not name lansoprazole. The lansoprazole label: “Decreased and delayed absorption of lansoprazole.”
Check it at the source: the lansoprazole FDA label on DailyMed (effective June 24, 2025, L. Perrigo Company); the sucralfate FDA label on DailyMed (effective September 2, 2026, Preferred Pharmaceuticals Inc.).
What does the lansoprazole label say about sucralfate?
Lansoprazole label, drug interactions (prescription label)Sucralfate Clinical Impact: Decreased and delayed absorption of lansoprazole. Intervention: Take PREVACID or PREVACID SoluTab at least 30 minutes prior to sucralfate [see ].
Source: FDA drug label (Prevacid 24 HR), L. Perrigo Company, effective June 24, 2025 (SPL set 205c9c1e-b422-4e86-a4b0-714b608adc19), via openFDA; the full label on DailyMed
What does the sucralfate label say about lansoprazole?
Sucralfate's label (effective September 2, 2026) and its 1 other brand-application label do not name lansoprazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Sucralfate), NDA018333 (Abbvie), as published by Preferred Pharmaceuticals Inc., effective September 2, 2026 (SPL set 536b8c00-13ab-4397-a754-63a1c92bf883), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lansoprazole | Sucralfate | |
|---|---|---|
| Labeled for | Acid reflux and ulcers | Acid reflux and ulcers |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.106 per capsule 30 mg capsule | $0.173 per tablet 1 g tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once