What the FDA labels say about taking them together
Lansoprazole and mycophenolic acid
Lansoprazole's FDA label of June 24, 2025 names mycophenolic acid in its drug interactions (prescription label) section; the mycophenolic acid label PlainMeds reads does not name lansoprazole. The lansoprazole label: “Lansoprazole can reduce the absorption of other drugs due to its effect on reducing intragastric acidity.”
Check it at the source: the lansoprazole FDA label on DailyMed (effective June 24, 2025, L. Perrigo Company); the mycophenolic acid FDA label on DailyMed (effective July 29, 2026, Novartis Pharmaceuticals Corporation).
What does the lansoprazole label say about mycophenolic acid?
Lansoprazole label, drug interactions (prescription label)Clinical Impact: Lansoprazole can reduce the absorption of other drugs due to its effect on reducing intragastric acidity. Intervention: Mycophenolate mofetil (MMF): Coadministration of PPIs in healthy subjects and in transplant patients receiving MMF has been reported to reduce the exposure to the active metabolite, mycophenolic acid (MPA), possibly due to a decrease in MMF solubility at an increased gastric pH. …
Source: FDA drug label (Prevacid 24 HR), L. Perrigo Company, effective June 24, 2025 (SPL set 205c9c1e-b422-4e86-a4b0-714b608adc19), via openFDA; the full label on DailyMed
What does the mycophenolic acid label say about lansoprazole?
Mycophenolic acid's label (effective July 29, 2026) does not name lansoprazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Myfortic), Novartis Pharmaceuticals Corporation, effective July 29, 2026 (SPL set eed26501-890d-4ff6-88e7-6dbea4726e53), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lansoprazole | Mycophenolic acid | |
|---|---|---|
| Labeled for | Acid reflux and ulcers | Organ transplant rejection |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.106 per capsule 30 mg capsule | $0.0996 per tablet 180 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once