What the FDA labels say about taking them together
Lansoprazole and mycophenolate mofetil
Lansoprazole's FDA label of June 24, 2025 names mycophenolate mofetil in its drug interactions (prescription label) section, and mycophenolate mofetil's label names lansoprazole too. The lansoprazole label: “Lansoprazole can reduce the absorption of other drugs due to its effect on reducing intragastric acidity.”
Check it at the source: the lansoprazole FDA label on DailyMed (effective June 24, 2025, L. Perrigo Company); the mycophenolate mofetil FDA label on DailyMed (effective August 5, 2026, Genentech, Inc.).
What does the lansoprazole label say about mycophenolate mofetil?
Lansoprazole label, drug interactions (prescription label)Clinical Impact: Lansoprazole can reduce the absorption of other drugs due to its effect on reducing intragastric acidity. Intervention: Mycophenolate mofetil (MMF): Coadministration of PPIs in healthy subjects and in transplant patients receiving MMF has been reported to reduce the exposure to the active metabolite, mycophenolic acid (MPA), possibly due to a decrease in MMF solubility at an increased gastric pH. …
Source: FDA drug label (Prevacid 24 HR), L. Perrigo Company, effective June 24, 2025 (SPL set 205c9c1e-b422-4e86-a4b0-714b608adc19), via openFDA; the full label on DailyMed
What does the mycophenolate mofetil label say about lansoprazole?
Mycophenolate mofetil label, drug interactionsExamples; Lansoprazole, pantoprazole
Source: FDA drug label (CellCept), NDA050722 (Roche Palo), as published by Genentech, Inc., effective August 5, 2026 (SPL set 37241e87-4af4-4dc3-a1aa-ea6f20d8dc40), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lansoprazole | Mycophenolate mofetil | |
|---|---|---|
| Labeled for | Acid reflux and ulcers | Organ transplant rejection |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.106 per capsule 30 mg capsule | $0.138 per capsule 250 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once