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What the FDA labels say about taking them together

Ketoconazole and ulipristal

Ulipristal's FDA label of July 20, 2026 names ketoconazole in its drug interactions section; the ketoconazole label PlainMeds reads does not name ulipristal. The ulipristal label: “Concentrations of ella Associated with Co-Administered Drugs CYP3A4 inhibitors such as itraconazole or ketoconazole increase plasma concentrations of ella.”

Check it at the source: the ketoconazole FDA label on DailyMed (effective January 28, 2026, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC); the ulipristal FDA label on DailyMed (effective July 20, 2026, PMI Branded Pharmaceuticals, Inc.).

What does the ketoconazole label say about ulipristal?

Ketoconazole's label (effective January 28, 2026) does not name ulipristal in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (ketoconazole), E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, effective January 28, 2026 (SPL set cad7c647-34a9-4e4e-83b3-8d78e58f588f), via openFDA; the full label on DailyMed

What does the ulipristal label say about ketoconazole?

Ulipristal label, drug interactions

Concentrations of ella Associated with Co-Administered Drugs CYP3A4 inhibitors such as itraconazole or ketoconazole increase plasma concentrations of ella [see Pharmacokinetics (12.3) ].

Source: FDA drug label (Ella), PMI Branded Pharmaceuticals, Inc., effective July 20, 2026 (SPL set 2bf93d23-cddd-4613-9066-5b5fa090404b), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

30Ketoconazole generic labelers
0Ulipristal generic labelers
KetoconazoleUlipristal
Labeled forFungal infectionsBirth control
Boxed warningNoNo
Pharmacy cost (NADAC)$0.249 per gram 2% cream$37.10 per tablet 30 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?