What the FDA labels say about taking them together
Ketamine and liothyronine
Liothyronine's FDA label of June 4, 2026 names ketamine in its drug interactions section; the ketamine label PlainMeds reads does not name liothyronine.
Check it at the source: the ketamine FDA label on DailyMed (effective March 27, 2026, Par Health USA, LLC); the liothyronine FDA label on DailyMed (effective June 4, 2026, Mylan Pharmaceuticals Inc.).
What does the ketamine label say about liothyronine?
Ketamine's label (effective March 27, 2026) does not name liothyronine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Ketalar), Par Health USA, LLC, effective March 27, 2026 (SPL set 14e8f864-8b8a-4e7e-8439-e510d3107063), via openFDA; the full label on DailyMed
What does the liothyronine label say about ketamine?
Liothyronine label, drug interactionsConcurrent use of ketamine and liothyronine sodium may produce marked hypertension and tachycardia.
Source: FDA drug label (Liothyronine Sodium), NDA010379 (King Pharms), as published by Mylan Pharmaceuticals Inc., effective June 4, 2026 (SPL set 115a84c2-0126-4dd7-816e-1873875f1e49), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ketamine | Liothyronine | |
|---|---|---|
| Labeled for | n/a | Hypothyroidism |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.556 per mL 500 mg/10 mL vial | $0.294 per tablet 25 mcg tablet |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once