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What the FDA labels say about taking them together

Ixazomib and rifampin

Ixazomib's FDA label of August 11, 2026 names rifampin in its drug interactions section; the rifampin label PlainMeds reads does not name ixazomib. The ixazomib label: “Avoid concomitant administration of NINLARO with strong CYP3A inducers.”

Check it at the source: the ixazomib FDA label on DailyMed (effective August 11, 2026, Takeda Pharmaceuticals America, Inc.); the rifampin FDA label on DailyMed (effective February 11, 2026, Lupin Pharmaceuticals, Inc.).

What does the ixazomib label say about rifampin?

Ixazomib label, drug interactions

Avoid concomitant administration of NINLARO with strong CYP3A inducers (such as rifampin, phenytoin, carbamazepine, and St. John's Wort) [see Clinical Pharmacology (12.3) ].

Source: FDA drug label (NINLARO), Takeda Pharmaceuticals America, Inc., effective August 11, 2026 (SPL set 038f2461-834b-4488-9ebd-863c83eef5a7), via openFDA; the full label on DailyMed

What does the rifampin label say about ixazomib?

Rifampin's label (effective February 11, 2026) does not name ixazomib in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (rifampin), Lupin Pharmaceuticals, Inc., effective February 11, 2026 (SPL set b56004f0-f23d-47f6-80c7-39884fccbccc), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Ixazomib generic labelers
13Rifampin generic labelers
IxazomibRifampin
Labeled forLeukemia, lymphoma and myeloman/a
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.679 per capsule 300 mg capsule
Shortage nowNo current entryIn shortage

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?