What the FDA labels say about taking them together
Itraconazole and tolterodine
Itraconazole's FDA label of July 13, 2026 names tolterodine in its drug interactions section, and tolterodine's label names itraconazole too. The itraconazole label: “Dutasteride Oxybutynin Sildenafil (for erectile dysfunction) Tadalafil Tolterodine Monitor for adverse reactions.”
Check it at the source: the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.); the tolterodine FDA label on DailyMed (effective February 9, 2026, Torrent Pharmaceuticals Limited).
What does the itraconazole label say about tolterodine?
Itraconazole label, drug interactionsDutasteride Oxybutynin Sildenafil (for erectile dysfunction) Tadalafil (for erectile dysfunction and benign prostatic hyperplasia) Tolterodine Monitor for adverse reactions.
Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed
What does the tolterodine label say about itraconazole?
Tolterodine label, drug interactionsFor patients receiving ketoconazole or other potent CYP3A4 inhibitors such as itraconazole, clarithromycin, or ritonavir, the recommended dose of tolterodine tartrate extended-release capsules is 2 mg once daily [ see DOSAGE AND ADMINISTRATION ( 2.2) and CLINICAL PHARMACOLOGY ( 12.3) ].
Detrol label (Viatris Specialty LLC, February 15, 2023), drug interactionsFor patients receiving ketoconazole or other potent CYP3A4 inhibitors such as other azole antifungals (e.g., itraconazole, miconazole) or macrolide antibiotics (e.g., erythromycin, clarithromycin) or cyclosporine or vinblastine, the recommended dose of DETROL is 1 mg twice daily (see DOSAGE AND ADMINISTRATION ).
Source: FDA drug label (Detrol, NDA020771), Viatris Specialty LLC, effective February 15, 2023 (SPL set 41eb00d2-64e3-4ec9-8732-4bfc81b04180), via openFDA
Source: FDA drug label (TOLTERODINE TARTRATE), Torrent Pharmaceuticals Limited, effective February 9, 2026 (SPL set db6e0b6d-0ce5-41d7-881f-881c11f530a4), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Itraconazole | Tolterodine | |
|---|---|---|
| Labeled for | Fungal infections | Overactive bladder |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.910 per capsule 100 mg capsule | $0.268 per capsule 2 mg capsule |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once