What the FDA labels say about taking them together
Itraconazole and talazoparib
Itraconazole's FDA label of July 13, 2026 names talazoparib in its drug interactions section, and talazoparib's label names itraconazole too. The talazoparib label: “Drugs on TALZENNA Effect of P-gp Inhibitors Breast Cancer Avoid coadministration of TALZENNA with the following P-gp inhibitors: itraconazole, amiodarone, carvedilol, clarithromycin, itraconazole, and verapamil.”
Check it at the source: the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.); the talazoparib FDA label on DailyMed (effective April 10, 2026, Pfizer Laboratories Div Pfizer Inc).
What does the itraconazole label say about talazoparib?
Itraconazole label, drug interactionsEntrectinib Pemigatinib Talazoparib Refer to the entrectinib, pemigatinib and talazoparib prescribing information for dosing instructions if concomitant use cannot be avoided.
Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed
What does the talazoparib label say about itraconazole?
Talazoparib label, drug interactionsDrugs on TALZENNA Effect of P-gp Inhibitors Breast Cancer Avoid coadministration of TALZENNA with the following P-gp inhibitors: itraconazole, amiodarone, carvedilol, clarithromycin, itraconazole, and verapamil.
Source: FDA drug label (Talzenna), Pfizer Laboratories Div Pfizer Inc, effective April 10, 2026 (SPL set c6fd147f-a77e-4a0b-9280-e82ecc41b4be), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Itraconazole | Talazoparib | |
|---|---|---|
| Labeled for | Fungal infections | Breast cancer, Prostate cancer |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.910 per capsule 100 mg capsule | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once