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What the FDA labels say about taking them together

Itraconazole and saxagliptin

Itraconazole's FDA label of July 13, 2026 names saxagliptin in its drug interactions section, and saxagliptin's label names itraconazole too. The itraconazole label: “Antidiabetic Drugs Repaglinide Saxagliptin Monitor for adverse reactions.”

Check it at the source: the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.); the saxagliptin FDA label on DailyMed (effective January 27, 2026, Glenmark Pharmaceuticals Inc., USA).

What does the itraconazole label say about saxagliptin?

Itraconazole label, drug interactions

Antidiabetic Drugs Repaglinide Saxagliptin Monitor for adverse reactions.

Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed

What does the saxagliptin label say about itraconazole?

Saxagliptin label, drug interactions

Similar significant increases in plasma concentrations of saxagliptin are anticipated with other strong CYP3A4/5 inhibitors (e.g., atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir, and telithromycin).

Source: FDA drug label (SAXAGLIPTIN), Glenmark Pharmaceuticals Inc., USA, effective January 27, 2026 (SPL set e286ffd4-c598-47fb-af06-2e15f7e6f99f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

11Itraconazole generic labelers
3Saxagliptin generic labelers
ItraconazoleSaxagliptin
Labeled forFungal infectionsType 2 diabetes
Boxed warningYesNo
Pharmacy cost (NADAC)$0.910 per capsule 100 mg capsule$1.04 per tablet 5 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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